Astragali Radix Isoflavones Synergistically Alleviate Cerebral Ischemia and Reperfusion Injury Via Activating Estrogen Receptor-PI3K-Akt Signaling Pathway

Isoflavones are major neuroprotective components of a medicinal herb Astragali Radix, against cerebral ischemia-reperfusion injury but the mechanisms of neuroprotection remain unclear. Calycosin and formononetin are two major AR isoflavones while daidzein is the metabolite of formononetin after abso...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Gu, Yong, Chen, Xi, Fu, Shuping, Liu, Wenlan, Wang, Qi, Liu, Ke-Jian, Shen, Jiangang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937971/
https://ncbi.nlm.nih.gov/pubmed/33692686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.533028
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