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Modeling Maturity Onset Diabetes of the Young in Pluripotent Stem Cells: Challenges and Achievements
Maturity onset diabetes of the young (MODY), is a group of monogenic diabetes disorders. Rodent models for MODY do not fully recapitulate the human phenotypes, calling for models generated in human cells. Human pluripotent stem cells (hPSCs), capable of differentiation towards pancreatic cells, poss...
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| Publicado no: | Front Endocrinol (Lausanne) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7937923/ https://ncbi.nlm.nih.gov/pubmed/33692757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.622940 |
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