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Human Pluripotent Stem Cells to Model Islet Defects in Diabetes

Diabetes mellitus is characterized by elevated levels of blood glucose and is ultimately caused by insufficient insulin production from pancreatic beta cells. Different research models have been utilized to unravel the molecular mechanisms leading to the onset of diabetes. The generation of pancreat...

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Détails bibliographiques
Publié dans:Front Endocrinol (Lausanne)
Auteurs principaux: Balboa, Diego, Iworima, Diepiriye G., Kieffer, Timothy J.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020750/
https://ncbi.nlm.nih.gov/pubmed/33828531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.642152
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