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The regulation of necroptosis by post-translational modifications

Necroptosis is a caspase-independent, lytic form of programmed cell death whose errant activation has been widely implicated in many pathologies. The pathway relies on the assembly of the apical protein kinases, RIPK1 and RIPK3, into a high molecular weight cytoplasmic complex, termed the necrosome,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Meng, Yanxiang, Sandow, Jarrod J., Czabotar, Peter E., Murphy, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937688/
https://ncbi.nlm.nih.gov/pubmed/33462412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00722-7
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