Hippocampal neurons isolated from rats subjected to the valproic acid model mimic in vivo synaptic pattern: evidence of neuronal priming during early development in autism spectrum disorders

BACKGROUND: Autism spectrum disorders (ASD) are synaptopathies characterized by area-specific synaptic alterations and neuroinflammation. Structural and adhesive features of hippocampal synapses have been described in the valproic acid (VPA) model. However, neuronal and microglial contribution to hi...

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Опубликовано в: :Mol Autism
Главные авторы: Traetta, Marianela Evelyn, Codagnone, Martín Gabriel, Uccelli, Nonthué Alejandra, Ramos, Alberto Javier, Zárate, Sandra, Reinés, Analía
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2021
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937248/
https://ncbi.nlm.nih.gov/pubmed/33676530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-021-00428-8
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