ELF3 activated by a superenhancer and an autoregulatory feedback loop is required for high-level HLA-C expression on extravillous trophoblasts

HLA-C arose during evolution of pregnancy in the great apes 10 to 15 million years ago. It has a dual function on placental extravillous trophoblasts (EVTs) as it contributes to both tolerance and immunity at the maternal–fetal interface. The mode of its regulation is of considerable interest in con...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Li, Qin, Meissner, Torsten B., Wang, Fang, Du, Ziming, Ma, Sai, Kshirsagar, Sarika, Tilburgs, Tamara, Buenrostro, Jason D., Uesugi, Motonari, Strominger, Jack L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936349/
https://ncbi.nlm.nih.gov/pubmed/33622787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025512118
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak