Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model

Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder characterized by progressive muscle degeneration and weakness due to mutations in the dystrophin gene. The symptoms of DMD share similarities with those of accelerated aging. Recently, hydrogen sulfide (H(2)S) supplementation has be...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ellwood, Rebecca A., Hewitt, Jennifer E., Torregrossa, Roberta, Philp, Ashleigh M., Hardee, Justin P., Hughes, Samantha, van de Klashorst, David, Gharahdaghi, Nima, Anupom, Taslim, Slade, Luke, Deane, Colleen S., Cooke, Michael, Etheridge, Timothy, Piasecki, Mathew, Antebi, Adam, Lynch, Gordon S., Philp, Andrew, Vanapalli, Siva A., Whiteman, Matthew, Szewczyk, Nathaniel J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936346/
https://ncbi.nlm.nih.gov/pubmed/33627403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018342118
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