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Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of Caenorhabditis elegans and its functional response to drugs

Muscle strength is a key clinical parameter used to monitor the progression of human muscular dystrophies, including Duchenne and Becker muscular dystrophies. Although Caenorhabditis elegans is an established genetic model for studying the mechanisms and treatments of muscular dystrophies, analogous...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Hewitt, Jennifer E., Pollard, Amelia K., Lesanpezeshki, Leila, Deane, Colleen S., Gaffney, Christopher J., Etheridge, Timothy, Szewczyk, Nathaniel J., Vanapalli, Siva A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307913/
https://ncbi.nlm.nih.gov/pubmed/30396907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.036137
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