Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of Caenorhabditis elegans and its functional response to drugs

Muscle strength is a key clinical parameter used to monitor the progression of human muscular dystrophies, including Duchenne and Becker muscular dystrophies. Although Caenorhabditis elegans is an established genetic model for studying the mechanisms and treatments of muscular dystrophies, analogous...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Hewitt, Jennifer E., Pollard, Amelia K., Lesanpezeshki, Leila, Deane, Colleen S., Gaffney, Christopher J., Etheridge, Timothy, Szewczyk, Nathaniel J., Vanapalli, Siva A.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307913/
https://ncbi.nlm.nih.gov/pubmed/30396907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.036137
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