α‐Emitting cancer therapy using (211)At‐AAMT targeting LAT1

α‐Methyl‐l‐tyrosine (AMT) has a high affinity for the cancer‐specific l‐type amino acid transporter 1 (LAT1). Therefore, we established an anti‐cancer therapy, with (211)At‐labeled α‐methyl‐l‐tyrosine ((211)At‐AAMT) as a carrier of (211)At into tumors. (211)At‐AAMT had high affinity for LAT1, inhibi...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Kaneda‐Nakashima, Kazuko, Zhang, ZiJian, Manabe, Yoshiyuki, Shimoyama, Atsushi, Kabayama, Kazuya, Watabe, Tadashi, Kanai, Yoshikatsu, Ooe, Kazuhiro, Toyoshima, Atsushi, Shirakami, Yoshifumi, Yoshimura, Takashi, Fukuda, Mitsuhiro, Hatazawa, Jun, Nakano, Takashi, Fukase, Koichi, Shinohara, Atsushi
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2021
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935802/
https://ncbi.nlm.nih.gov/pubmed/33277750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14761
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