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TARBP2 promotes tumor angiogenesis and metastasis by destabilizing antiangiogenic factor mRNAs

Tumor angiogenesis is a crucial step in the further growth and metastasis of solid tumors. However, its regulatory mechanism remains unclear. Here, we showed that TARBP2, an RNA‐binding protein, played a role in promoting tumor‐induced angiogenesis both in vitro and in vivo through degrading the mRN...

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Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Zhou, Meicen, Lu, Wenbao, Li, Bingwei, Liu, Xueting, Li, Ailing
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935780/
https://ncbi.nlm.nih.gov/pubmed/33484209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14820
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