Cyclic-di-GMP Induces STING-Dependent ILC2 to ILC1 Shift During Innate Type 2 Lung Inflammation

Type 2 inflammation is found in most forms of asthma, which may co-exist with recurrent viral infections, bacterial colonization, and host cell death. These processes drive the accumulation of intracellular cyclic-di-nucleotides such as cyclic-di-GMP (CDG). Group 2 innate lymphoid cells (ILC2s) are...

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Pubblicato in:Front Immunol
Autori principali: Cavagnero, Kellen J., Badrani, Jana H., Naji, Luay H., Amadeo, Michael B., Leng, Anthea S., Lacasa, Lee Diego, Strohm, Allyssa N., Renusch, Samantha R., Gasparian, Suzanna S., Doherty, Taylor A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935536/
https://ncbi.nlm.nih.gov/pubmed/33679760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.618807
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