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Histone deacetylase inhibitor during in vitro maturation decreases developmental capacity of bovine oocytes

This study aimed to evaluate the effect of scriptaid during pre-maturation (PIVM) and/or maturation (IVM) on developmental competence of bovine oocytes. Cumulus-oocyte complexes (COCs) were submitted to PIVM for 6 h in the presence or absence of scriptaid. COCs were distributed into five groups: T1-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pontelo, Thais Preisser, Franco, Mauricio Machaim, Kawamoto, Taynan Stonoga, Caixeta, Felippe Manoel Costa, de Oliveira Leme, Ligiane, Kussano, Nayara Ribeiro, Zangeronimo, Marcio Gilberto, Dode, Margot Alves Nunes
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935280/
https://ncbi.nlm.nih.gov/pubmed/33667248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247518
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