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Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity

Morbilliviruses, such as measles virus (MeV) and canine distemper virus (CDV), are highly infectious members of the paramyxovirus family. MeV is responsible for major morbidity and mortality in non-vaccinated populations. ERDRP-0519, a pan-morbillivirus small molecule inhibitor for the treatment of...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Cox, Robert M., Sourimant, Julien, Govindarajan, Mugunthan, Natchus, Michael G., Plemper, Richard K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935272/
https://ncbi.nlm.nih.gov/pubmed/33621266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009371
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