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Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity
Morbilliviruses, such as measles virus (MeV) and canine distemper virus (CDV), are highly infectious members of the paramyxovirus family. MeV is responsible for major morbidity and mortality in non-vaccinated populations. ERDRP-0519, a pan-morbillivirus small molecule inhibitor for the treatment of...
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| Udgivet i: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7935272/ https://ncbi.nlm.nih.gov/pubmed/33621266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009371 |
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