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Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity

Morbilliviruses, such as measles virus (MeV) and canine distemper virus (CDV), are highly infectious members of the paramyxovirus family. MeV is responsible for major morbidity and mortality in non-vaccinated populations. ERDRP-0519, a pan-morbillivirus small molecule inhibitor for the treatment of...

詳細記述

保存先:
書誌詳細
出版年:PLoS Pathog
主要な著者: Cox, Robert M., Sourimant, Julien, Govindarajan, Mugunthan, Natchus, Michael G., Plemper, Richard K.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935272/
https://ncbi.nlm.nih.gov/pubmed/33621266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009371
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