Patterns of Resistance Differ in Patients with Acute Myeloid Leukemia Treated with Type I versus Type II FLT3 Inhibitors

Despite promising results with FLT3 inhibitors (FLT3i), response durations remain short. We studied pretreatment and relapse bone marrow samples from patients with FLT3-mutated acute myeloid leukemia (AML) treated with FLT3i-based therapies (secondary resistance cohort), and pretreatment bone marrow...

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Bibliografiska uppgifter
I publikationen:Blood Cancer Discov
Huvudupphovsmän: Alotaibi, Ahmad S., Yilmaz, Musa, Kanagal-Shamanna, Rashmi, Loghavi, Sanam, Kadia, Tapan M., DiNardo, Courtney D., Borthakur, Gautam, Konopleva, Marina, Pierce, Sherry A., Wang, Sa A., Tang, Guilin, Guerra, Veronica, Samra, Bachar, Pemmaraju, Naveen, Jabbour, Elias, Short, Nicholas J., Issa, Ghayas C., Ohanian, Maro, Garcia-Manero, Guillermo, Bhalla, Kapil N., Patel, Keyur P., Takahashi, Koichi, Andreeff, Michael, Cortes, Jorge E., Kantarjian, Hagop M., Ravandi, Farhad, Daver, Naval
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Association for Cancer Research 2020
Ämnen:
Research Brief
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935111/
https://ncbi.nlm.nih.gov/pubmed/33681815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-20-0143
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