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Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities

The transcriptomic classification of glioblastoma (GBM) has failed to predict survival and therapeutic vulnerabilities. A computational approach for unbiased identification of core biological traits of single cells and bulk tumors uncovered four tumor cell states and GBM subtypes distributed along n...

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Detalhes bibliográficos
Publicado no:Nat Cancer
Main Authors: Garofano, Luciano, Migliozzi, Simona, Oh, Young Taek, D’Angelo, Fulvio, Najac, Ryan D., Ko, Aram, Frangaj, Brulinda, Caruso, Francesca Pia, Yu, Kai, Yuan, Jinzhou, Zhao, Wenting, Di Stefano, Anna Luisa, Bielle, Franck, Jiang, Tao, Sims, Peter, Suvà, Mario L., Tang, Fuchou, Su, Xiao-Dong, Ceccarelli, Michele, Sanson, Marc, Lasorella, Anna, Iavarone, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935068/
https://ncbi.nlm.nih.gov/pubmed/33681822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-020-00159-4
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