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n-Propyl 6-amino-2,6-dideoxy-2,2-difluoro-β-d-glucopyranoside is a good inhibitor for the β-galactosidase from E. coli

A convenient route has been developed for the synthesis of novel 6-amino-2,2-(or 3,3-difluoro)-2-(or 3),6-dideoxy-hexopyranoses. Biological screening showed these compounds as good inhibitors for several glycosidases. Especially n-propyl 6-amino-2,6-dideoxy-2,2-difluoro-β-d-glucopyranoside (8) was a...

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Détails bibliographiques
Publié dans:Med Chem Res
Auteurs principaux: Serbian, Immo, Prell, Erik, Fischer, Claudia, Deigner, Hans-Peter, Csuk, René
Format: Artigo
Langue:Inglês
Publié: Springer US 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934981/
https://ncbi.nlm.nih.gov/pubmed/33716475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-021-02715-8
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