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Evaluating the Genomic Parameters Governing rAAV-Mediated Homologous Recombination
Recombinant adeno-associated virus (rAAV) vectors have the unique ability to promote targeted integration of transgenes via homologous recombination at specified genomic sites, reaching frequencies of 0.1%–1%. We studied genomic parameters that influence targeting efficiencies on a large scale. To d...
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| 出版年: | Mol Ther |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Gene & Cell Therapy
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7934627/ https://ncbi.nlm.nih.gov/pubmed/33248247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.11.025 |
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