Inhibition of lncRNA Gm15834 Attenuates Autophagy-Mediated Myocardial Hypertrophy via the miR-30b-3p/ULK1 Axis in Mice

Emerging evidence reveals that autophagy plays crucial roles in cardiac hypertrophy. Long noncoding RNAs (lncRNAs) are novel transcripts that function as gene regulators. However, it is unclear whether lncRNAs regulate autophagy in cardiac hypertrophy. Here, we identified a novel transcript named ln...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Song, Chao, Qi, Hanping, Liu, Yongsheng, Chen, Yunping, Shi, Pilong, Zhang, Shu, Ren, Jing, Wang, Lixin, Cao, Yonggang, Sun, Hongli
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934579/
https://ncbi.nlm.nih.gov/pubmed/33130312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.10.024
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