Inhibition of BCL11B induces downregulation of PTK7 and results in growth retardation and apoptosis in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive subtype of leukemia with poor prognosis, and biomarkers and novel therapeutic targets are urgently needed for this disease. Our previous studies have found that inhibition of the B-cell leukemia/lymphoma 11B (BCL11B) gene could significant...

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Detalhes bibliográficos
Publicado no:Biomark Res
Main Authors: Li, Kehan, Chen, Cunte, Gao, Rili, Yu, Xibao, Huang, Youxue, Chen, Zheng, Liu, Zhuandi, Chen, Shaohua, Luo, Gengxin, Huang, Xin, Przybylski, Grzegorz K., Li, Yangqiu, Zeng, Chengwu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934371/
https://ncbi.nlm.nih.gov/pubmed/33663588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-021-00270-3
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