Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia

BACKGROUND: Acute promyelocytic leukemia (APL) is associated with chromosomal translocation t(15;17), which results in the proliferation of morphologically abnormal promyelocytes. Gain of supernumerary copies of the 8q24 chromosomal region, which harbors MYC and PVT1, has been shown to be the most c...

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Bibliografske podrobnosti
izdano v:J Hematol Oncol
Main Authors: Zeng, Chengwu, Yu, Xibao, Lai, Jing, Yang, Lijiang, Chen, Shaohua, Li, Yangqiu
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Rapid Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636781/
https://ncbi.nlm.nih.gov/pubmed/26545364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0223-4
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