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Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia

BACKGROUND: Acute promyelocytic leukemia (APL) is associated with chromosomal translocation t(15;17), which results in the proliferation of morphologically abnormal promyelocytes. Gain of supernumerary copies of the 8q24 chromosomal region, which harbors MYC and PVT1, has been shown to be the most c...

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Dettagli Bibliografici
Pubblicato in:J Hematol Oncol
Autori principali: Zeng, Chengwu, Yu, Xibao, Lai, Jing, Yang, Lijiang, Chen, Shaohua, Li, Yangqiu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636781/
https://ncbi.nlm.nih.gov/pubmed/26545364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0223-4
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