Inhibition of long non-coding RNA NEAT1 impairs myeloid differentiation in acute promyelocytic leukemia cells

BACKGROUND: Acute promyelocytic leukemia (APL) is characterized by the reciprocal translocation t(15;17), which fuses PML with retinoic acid receptor alpha (RARα). Although PML-RARα is crucially important for pathogenesis and responsiveness to treatment, the molecular and cellular mechanisms by whic...

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Main Authors: Zeng, Chengwu, Xu, Yan, Xu, Ling, Yu, Xibao, Cheng, Jingjing, Yang, Lijian, Chen, Shaohua, Li, Yangqiu
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180842/
https://ncbi.nlm.nih.gov/pubmed/25245097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-693
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