Hypermethylation of heparanase 2 promotes colorectal cancer proliferation and is associated with poor prognosis

BACKGROUND: The epigenetic abnormality of tumor-associated genes contributes to the pathogenesis of colorectal carcinoma (CRC). However, methylation in colorectal cancer is still poorly characterized. METHOD: By integration of DNA methylation data from the GEO database and gene expression data from...

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Bibliografski detalji
Izdano u:J Transl Med
Glavni autori: Zhang, Hui, Xu, Chenxin, Shi, Chen, Zhang, Junying, Qian, Ting, Wang, Zhuo, Ma, Rong, Wu, Jianzhong, Jiang, Feng, Feng, Jifeng
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934273/
https://ncbi.nlm.nih.gov/pubmed/33663522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02770-0
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