Allele Loss and Down-Regulation of Heparanase Gene Are Associated with the Progression and Poor Prognosis of Hepatocellular Carcinoma

OBJECTIVES: The role of heparanase (HPSE) gene in cancers including hepatocellular carcinoma (HCC) is currently controversial. This study was aimed at investigating the impact of genetic alteration and expression change of HPSE on the progression and prognosis of HCC. METHODS: The HPSE gene was stud...

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Main Authors: Huang, Guo-Liang, Li, Bin-Kui, Zhang, Mei-Yin, Wei, Rong-Rong, Yuan, Yun-Fei, Shi, Ming, Chen, Xiao-Qian, Huang, Long, Zhang, Hui-Zhong, Liu, Wanqing, Huang, Bi-Jun, Li, Honghua, Zheng, Xiao-Feng, Luo, Xian-Rong, Wang, Hui-Yun
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432106/
https://ncbi.nlm.nih.gov/pubmed/22952874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044061
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