Allele Loss and Down-Regulation of Heparanase Gene Are Associated with the Progression and Poor Prognosis of Hepatocellular Carcinoma

OBJECTIVES: The role of heparanase (HPSE) gene in cancers including hepatocellular carcinoma (HCC) is currently controversial. This study was aimed at investigating the impact of genetic alteration and expression change of HPSE on the progression and prognosis of HCC. METHODS: The HPSE gene was stud...

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Detalhes bibliográficos
Main Authors: Huang, Guo-Liang, Li, Bin-Kui, Zhang, Mei-Yin, Wei, Rong-Rong, Yuan, Yun-Fei, Shi, Ming, Chen, Xiao-Qian, Huang, Long, Zhang, Hui-Zhong, Liu, Wanqing, Huang, Bi-Jun, Li, Honghua, Zheng, Xiao-Feng, Luo, Xian-Rong, Wang, Hui-Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432106/
https://ncbi.nlm.nih.gov/pubmed/22952874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044061
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