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Challenges of applying multicellular tumor spheroids in preclinical phase

The three-dimensional (3D) multicellular tumor spheroids (MCTs) model is becoming an essential tool in cancer research as it expresses an intermediate complexity between 2D monolayer models and in vivo solid tumors. MCTs closely resemble in vivo solid tumors in many aspects, such as the heterogeneou...

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Bibliografiske detaljer
Udgivet i:Cancer Cell Int
Main Authors: Han, Se Jik, Kwon, Sangwoo, Kim, Kyung Sook
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934264/
https://ncbi.nlm.nih.gov/pubmed/33663530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-021-01853-8
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