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Challenges of applying multicellular tumor spheroids in preclinical phase

The three-dimensional (3D) multicellular tumor spheroids (MCTs) model is becoming an essential tool in cancer research as it expresses an intermediate complexity between 2D monolayer models and in vivo solid tumors. MCTs closely resemble in vivo solid tumors in many aspects, such as the heterogeneou...

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Dettagli Bibliografici
Pubblicato in:Cancer Cell Int
Autori principali: Han, Se Jik, Kwon, Sangwoo, Kim, Kyung Sook
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934264/
https://ncbi.nlm.nih.gov/pubmed/33663530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-021-01853-8
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