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Challenges of applying multicellular tumor spheroids in preclinical phase

The three-dimensional (3D) multicellular tumor spheroids (MCTs) model is becoming an essential tool in cancer research as it expresses an intermediate complexity between 2D monolayer models and in vivo solid tumors. MCTs closely resemble in vivo solid tumors in many aspects, such as the heterogeneou...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Han, Se Jik, Kwon, Sangwoo, Kim, Kyung Sook
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934264/
https://ncbi.nlm.nih.gov/pubmed/33663530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-021-01853-8
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