Interaction with single-stranded DNA-binding protein localizes ribonuclease HI to DNA replication forks and facilitates R-loop removal

DNA replication complexes (replisomes) routinely encounter proteins and unusual nucleic acid structures that can impede their progress. Barriers can include transcription complexes and R-loops that form when RNA hybridizes with complementary DNA templates behind RNA polymerases. Cells encode several...

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Dettagli Bibliografici
Pubblicato in:Mol Microbiol
Autori principali: Wolak, Christine, Ma, Hui Jun, Soubry, Nicolas, Sandler, Steven J., Reyes-Lamothe, Rodrigo, Keck, James L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934204/
https://ncbi.nlm.nih.gov/pubmed/32426857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14529
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