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The Synergistic Effect of PARP Inhibitors and Immune Checkpoint Inhibitors
Poly (ADP-ribose) polymerase (PARP) inhibitors have demonstrated great promise for treating cancers with homologous recombination (HR) defects, such as germline BRCA1/2 mutation. Further studies suggest that PARP inhibitors (PARPi) can also exhibit efficacy in HR-competent cancers, by amplifying the...
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| Wydane w: | Clin Med Insights Oncol |
|---|---|
| Główni autorzy: | , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
SAGE Publications
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7934064/ https://ncbi.nlm.nih.gov/pubmed/33737855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179554921996288 |
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