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The Synergistic Effect of PARP Inhibitors and Immune Checkpoint Inhibitors

Poly (ADP-ribose) polymerase (PARP) inhibitors have demonstrated great promise for treating cancers with homologous recombination (HR) defects, such as germline BRCA1/2 mutation. Further studies suggest that PARP inhibitors (PARPi) can also exhibit efficacy in HR-competent cancers, by amplifying the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Med Insights Oncol
Main Authors: Wu, Zhaozhen, Cui, Pengfei, Tao, Haitao, Zhang, Sujie, Ma, Junxun, Liu, Zhefeng, Wang, Jinliang, Qian, Yuanyu, Chen, Shixue, Huang, Ziwei, Zheng, Xuan, Huang, Di, Hu, Yi
פורמט: Artigo
שפה:Inglês
יצא לאור: SAGE Publications 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934064/
https://ncbi.nlm.nih.gov/pubmed/33737855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179554921996288
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