The Synergistic Effect of PARP Inhibitors and Immune Checkpoint Inhibitors

Poly (ADP-ribose) polymerase (PARP) inhibitors have demonstrated great promise for treating cancers with homologous recombination (HR) defects, such as germline BRCA1/2 mutation. Further studies suggest that PARP inhibitors (PARPi) can also exhibit efficacy in HR-competent cancers, by amplifying the...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Med Insights Oncol
Hauptverfasser: Wu, Zhaozhen, Cui, Pengfei, Tao, Haitao, Zhang, Sujie, Ma, Junxun, Liu, Zhefeng, Wang, Jinliang, Qian, Yuanyu, Chen, Shixue, Huang, Ziwei, Zheng, Xuan, Huang, Di, Hu, Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2021
Schlagworte:
Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934064/
https://ncbi.nlm.nih.gov/pubmed/33737855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179554921996288
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