Circulating clonally expanded T cells reflect functions of tumor-infiltrating T cells

Understanding the relationship between tumor and peripheral immune environments could allow longitudinal immune monitoring in cancer. Here, we examined whether T cells that share the same TCRαβ and are found in both tumor and blood can be interrogated to gain insight into the ongoing tumor T cell re...

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Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Lucca, Liliana E., Axisa, Pierre-Paul, Lu, Benjamin, Harnett, Brian, Jessel, Shlomit, Zhang, Le, Raddassi, Khadir, Zhang, Lin, Olino, Kelly, Clune, James, Singer, Meromit, Kluger, Harriet M., Hafler, David A.
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2021
Sujets:
Brief Definitive Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933991/
https://ncbi.nlm.nih.gov/pubmed/33651881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200921
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