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Immunodominant antibody germlines in COVID-19

The neutralizing antibody response to SARS-CoV-2 is dominated by antibodies deriving from germlines IGHV3-53/IGHV3-66, which are also associated with self-reacting antibodies. Could vaccines avoid the expansion of this immunodominant response, decrease the risk of autoimmunity, and still protect aga...

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Bibliografski detalji
Izdano u:J Exp Med
Glavni autori: Andreano, Emanuele, Rappuoli, Rino
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933983/
https://ncbi.nlm.nih.gov/pubmed/33656515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20210281
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