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Immunodominant antibody germlines in COVID-19
The neutralizing antibody response to SARS-CoV-2 is dominated by antibodies deriving from germlines IGHV3-53/IGHV3-66, which are also associated with self-reacting antibodies. Could vaccines avoid the expansion of this immunodominant response, decrease the risk of autoimmunity, and still protect aga...
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| Udgivet i: | J Exp Med |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Rockefeller University Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7933983/ https://ncbi.nlm.nih.gov/pubmed/33656515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20210281 |
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