Transgenic overexpression of ITGB6 in intestinal epithelial cells exacerbates dextran sulfate sodium‐induced colitis in mice

Integrins, as a large family of cell adhesion molecules, play a crucial role in maintaining intestinal homeostasis. In inflammatory bowel disease (IBD), homeostasis is disrupted. Integrin αvβ6, which is mainly regulated by the integrin β6 subunit gene (ITGB6), is a cell adhesion molecule that mediat...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Chen, Haiyan, Chen, Liubo, Wang, Xin, Ge, Xiaoxu, Sun, Lifeng, Wang, Zhanhuai, Xu, Xiaoming, Song, Yongmao, Chen, Jing, Deng, Qun, Xie, Haiting, Chen, Ting, Chen, Yan, Ding, Kefeng, Wu, Jingjing, Wang, Jian
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933932/
https://ncbi.nlm.nih.gov/pubmed/33491282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16297
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