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A combination of sorafenib and radiotherapy reduces NF-κB activity and growth of hepatocellular carcinoma in an orthotopic mouse model

Hepatocellular carcinoma (HCC) is difficult to diagnose at an early stage, and its prognosis is generally poor. Sorafenib is the primary treatment for unresectable advanced HCC and targets multiple receptor tyrosine kinases. However, sorafenib only extends the average survival time by 3 months. This...

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Dades bibliogràfiques
Publicat a:Oncol Lett
Autors principals: Chuang, Hui-Yen, Tyan, Yeu-Sheng, Hwang, Jeng-Jong, Shih, Kuang-Chung, Lin, Wei-Chan
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933744/
https://ncbi.nlm.nih.gov/pubmed/33692869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12598
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