G Protein-Coupled Estrogen Receptor Correlates With Dkk2 Expression and Has Prognostic Impact in Ovarian Cancer Patients

PURPOSE: Wnt pathway modulator Dickkopf 2 (Dkk2) and signaling of the G protein-coupled estrogen receptor (GPER) seem to have essential functions in numerous cancer types. For epithelial ovarian cancer (EOC), it has not been proven if either Dkk2 or the GPER on its own have an independent impact on...

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Dettagli Bibliografici
Pubblicato in:Front Endocrinol (Lausanne)
Autori principali: Fraungruber, Patricia, Kaltofen, Till, Heublein, Sabine, Kuhn, Christina, Mayr, Doris, Burges, Alexander, Mahner, Sven, Rathert, Philipp, Jeschke, Udo, Trillsch, Fabian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Endocrinology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933595/
https://ncbi.nlm.nih.gov/pubmed/33679613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.564002
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