G Protein-Coupled Estrogen Receptor Correlates With Dkk2 Expression and Has Prognostic Impact in Ovarian Cancer Patients

PURPOSE: Wnt pathway modulator Dickkopf 2 (Dkk2) and signaling of the G protein-coupled estrogen receptor (GPER) seem to have essential functions in numerous cancer types. For epithelial ovarian cancer (EOC), it has not been proven if either Dkk2 or the GPER on its own have an independent impact on...

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Vydáno v:Front Endocrinol (Lausanne)
Hlavní autoři: Fraungruber, Patricia, Kaltofen, Till, Heublein, Sabine, Kuhn, Christina, Mayr, Doris, Burges, Alexander, Mahner, Sven, Rathert, Philipp, Jeschke, Udo, Trillsch, Fabian
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933595/
https://ncbi.nlm.nih.gov/pubmed/33679613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.564002
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