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Massively Parallel Sequencing for Rare Genetic Disorders: Potential and Pitfalls

There have been two major eras in the history of gene discovery. The first was the era of linkage analysis, with approximately 1,300 disease-related genes identified by positional cloning by the turn of the millennium. The second era has been powered by two major breakthroughs: the publication of th...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: McInerney-Leo, Aideen M., Duncan, Emma L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933540/
https://ncbi.nlm.nih.gov/pubmed/33679611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.628946
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