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Preparation of co-crystals of human PPARα-LBD and ligand for high-resolution X-ray crystallography

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptor-type transcription factors with three subtypes (α, δ, and γ) that regulate cell differentiation and metabolism. Co-crystals of human PPARα-ligand-binding domain (LBD)-PPARα ligand for X-ray crystallography have been difficult t...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:STAR Protoc
Autori principali: Kamata, Shotaro, Oyama, Takuji, Ishii, Isao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933539/
https://ncbi.nlm.nih.gov/pubmed/33718889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100364
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