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Protein crystallization: Eluding the bottleneck of X-ray crystallography

To date, X-ray crystallography remains the gold standard for the determination of macromolecular structure and protein substrate interactions. However, the unpredictability of obtaining a protein crystal remains the limiting factor and continues to be the bottleneck in determining protein structures...

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Publicat a:AIMS Biophys
Autors principals: Holcomb, Joshua, Spellmon, Nicholas, Zhang, Yingxue, Doughan, Maysaa, Li, Chunying, Yang, Zhe
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645037/
https://ncbi.nlm.nih.gov/pubmed/29051919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3934/biophy.2017.4.557
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