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Using the Microwell-mesh to culture microtissues in vitro and as a carrier to implant microtissues in vivo into mice

Prostate cancer (PCa) patient-derived xenografts (PDXs) are commonly propagated by serial transplantation of “pieces” of tumour in mice, but the cellular composition of pieces is not standardised. Herein, we optimised a microwell platform, the Microwell-mesh, to aggregate precise numbers of cells in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Monterosso, Melissa E., Futrega, Kathryn, Lott, William B., Vela, Ian, Williams, Elizabeth D., Doran, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933425/
https://ncbi.nlm.nih.gov/pubmed/33664329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84154-4
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