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How transcription factors drive choice of T cell fate

Recent evidence has elucidated how multipotent blood progenitors transform their identities in the thymus and undergo commitment to become T cells. Together with environmental signalling, a core group of transcription factors have essential roles in this process by directly activating and repressing...

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Bibliographic Details
Published in:Nat Rev Immunol
Main Authors: Hosokawa, Hiroyuki, Rothenberg, Ellen V.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933071/
https://ncbi.nlm.nih.gov/pubmed/32918063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-020-00426-6
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