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Cytokines, Transcription Factors, and the Initiation of T-Cell Development

Multipotent blood progenitor cells migrate into the thymus and initiate the T-cell differentiation program. T-cell progenitor cells gradually acquire T-cell characteristics while shedding their multipotentiality for alternative fates. This process is supported by extracellular signaling molecules, i...

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Détails bibliographiques
Publié dans:Cold Spring Harb Perspect Biol
Auteurs principaux: Hosokawa, Hiroyuki, Rothenberg, Ellen V.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876153/
https://ncbi.nlm.nih.gov/pubmed/28716889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a028621
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