Effector memory CD8 T cell response elicits Hepatitis E Virus genotype 3 pathogenesis in the elderly

Genotype 3 Hepatitis E virus (HEV-3) is an emerging threat for aging population. More than one third of older infected patients develops clinical symptoms with severe liver damage, while others remain asymptomatic. The origin of this discrepancy is still elusive although HEV-3 pathogenesis appears t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: El Costa, Hicham, Gouilly, Jordi, Abravanel, Florence, Bahraoui, Elmostafa, Peron, Jean-Marie, Kamar, Nassim, Jabrane-Ferrat, Nabila, Izopet, Jacques
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932504/
https://ncbi.nlm.nih.gov/pubmed/33617602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009367
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