Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface

Hepatitis E virus (HEV) infection, particularly HEV genotype 1 (HEV-1), can result in fulminant hepatic failure and severe placental diseases, but mechanisms underlying genotype-specific pathogenicity are unclear and appropriate models are lacking. Here, we model HEV-1 infection ex vivo at the mater...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gouilly, Jordi, Chen, Qian, Siewiera, Johan, Cartron, Géraldine, Levy, Claude, Dubois, Martine, Al-Daccak, Reem, Izopet, Jacques, Jabrane-Ferrat, Nabila, El Costa, Hicham
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232144/
https://ncbi.nlm.nih.gov/pubmed/30420629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07200-2
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