Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling

Early assessment of adverse drug effects in humans is critical to avoid long-lasting harm. However, current approaches for early detection of adverse effects still lack predictive and organ-specific biomarkers to evaluate undesired responses in humans. Microphysiological systems (MPSs) are in vitro...

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Bibliografske podrobnosti
izdano v:Front Big Data
Main Authors: Mina, Sara G., Alaybeyoglu, Begum, Murphy, William L., Thomson, James A., Stokes, Cynthia L., Cirit, Murat
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Big Data
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931859/
https://ncbi.nlm.nih.gov/pubmed/33693346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fdata.2019.00023
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