Monitoring Anti-tuberculosis Treatment Response Using Analysis of Whole Blood Mycobacterium tuberculosis Specific T Cell Activation and Functional Markers

BACKGROUND: Blood-based biomarkers have been proposed as an alternative to current sputum-based treatment monitoring methods in active tuberculosis (ATB). The aim of this study was to validate previously described phenotypic, activation, and cytokine markers of treatment response in a West African c...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Vickers, Molly A., Darboe, Fatoumatta, Muefong, Caleb N., Mbayo, Georgetta, Barry, Amadou, Gindeh, Awa, Njie, Sainabou, Riley, Abi-Janet, Sarr, Binta, Sambou, Basil, Dockrell, Hazel M., Charalambous, Salome, Rachow, Andrea, Owolabi, Olumuyiwa, Jayasooriya, Shamanthi, Sutherland, Jayne S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931252/
https://ncbi.nlm.nih.gov/pubmed/33679684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.572620
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