M. tuberculosis T cell epitope analysis reveals paucity of antigenic variation and identifies rare variable TB antigens

Pathogens that evade adaptive immunity typically exhibit antigenic variation. By contrast, it appears that although the chronic human tuberculosis (TB)-causing pathogen Mycobacterium tuberculosis needs to counter host T cell responses, its T cell epitopes are hyperconserved. Here we present an exten...

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Detaylı Bibliyografya
Yayımlandı:Cell Host Microbe
Asıl Yazarlar: Coscolla, Mireia, Copin, Richard, Sutherland, Jayne, Gehre, Florian, de Jong, Bouke, Owolabi, Olumuiya, Mbayo, Georgetta, Giardina, Federica, Ernst, Joel D., Gagneux, Sebastien
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758912/
https://ncbi.nlm.nih.gov/pubmed/26607161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.10.008
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