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Structural snapshots of the kinesin‐2 OSM‐3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism

Motile kinesins are motor proteins that translocate along microtubules as they hydrolyze ATP. They share a conserved motor domain which harbors both ATPase and microtubule‐binding activities. An ATP hydrolysis mechanism involving two water molecules has been proposed based on the structure of the ki...

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Publicado en:FEBS Open Bio
Autores principales: Varela, Paloma F., Chenon, Mélanie, Velours, Christophe, Verhey, Kristen J., Ménétrey, Julie, Gigant, Benoît
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931232/
https://ncbi.nlm.nih.gov/pubmed/33513284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13101
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