Characterization of the binding mode of JNK-interacting protein 1 (JIP1) to kinesin-light chain 1 (KLC1)

JIP1 was first identified as scaffold protein for the MAP kinase JNK and is a cargo protein for the kinesin1 molecular motor. JIP1 plays significant and broad roles in neurons, mainly as a regulator of kinesin1-dependent transport, and is associated with human pathologies such as cancer and Alzheime...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Nguyen, T. Quyen, Aumont-Nicaise, Magali, Andreani, Jessica, Velours, Christophe, Chenon, Mélanie, Vilela, Fernando, Geneste, Clémentine, Varela, Paloma F., Llinas, Paola, Ménétrey, Julie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Molecular Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130945/
https://ncbi.nlm.nih.gov/pubmed/30026235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003916
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