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In vivo Genome Editing Therapeutic Approaches for Neurological Disorders: Where Are We in the Translational Pipeline?

In vivo genome editing tools, such as those based on CRISPR, have been increasingly utilized in both basic and translational neuroscience research. There are currently nine in vivo non-CNS genome editing therapies in clinical trials, and the pre-clinical pipeline of major biotechnology companies dem...

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Bibliografiske detaljer
Udgivet i:Front Neurosci
Main Authors: Lubroth, Pablo, Colasante, Gaia, Lignani, Gabriele
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930815/
https://ncbi.nlm.nih.gov/pubmed/33679313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.632522
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