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In vivo Genome Editing Therapeutic Approaches for Neurological Disorders: Where Are We in the Translational Pipeline?

In vivo genome editing tools, such as those based on CRISPR, have been increasingly utilized in both basic and translational neuroscience research. There are currently nine in vivo non-CNS genome editing therapies in clinical trials, and the pre-clinical pipeline of major biotechnology companies dem...

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Vydáno v:Front Neurosci
Hlavní autoři: Lubroth, Pablo, Colasante, Gaia, Lignani, Gabriele
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930815/
https://ncbi.nlm.nih.gov/pubmed/33679313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.632522
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